Arsenic aggravated reproductive toxicity in male rats exposed to lead during the perinatal period
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چکیده
منابع مشابه
perinatal period . Lead in teeth during the
IN a survey of the paediatric significance of environmental lead there was evidence that part of the maternal intake of lead may influence the fetus' (Barltrop, 1969). Lead is incorporated in calcified tissues, and the studies of Altshuller, Halak and Landing (1962) andof Needleman, Tuncay and Shapiro (1972) indicate that the primary teeth provide evidence of lead exposure during infancy, a typ...
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Chronic developmental lead (Pb) exposure has long been associated with cognitive dysfunction in children and animals. N-methyl-D-aspartate (NMDA) receptors, important in the synaptic mechanisms involved in learning and memory, are key target of lead toxicity. D-cycloserine (DCS), a partial agonist of the NMDAAuteur correspondant: [email protected] (Khaled Kahloula) Université Badji Mokhtar An...
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most serious problem that leads to reproductive system failure in both human and animals. Present study was carried out to investigate whether hydroalcholic extract of Dorema aucheri leaves could protect the male rats against lead-induced reproductive toxicity. Materials and Methods: Adult wistar rats were treated with 0.1% lead acetate in drinking water with or without 100, 200 and 400 mg/kg D...
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Male infertility accounts for about 50% of infertility cases [1]. Anatomic, genetic, endocrinological, environmental, behavioral and nutritional imbalances are critical causes of male infertility [2-5]. Therapeutic drugs can also adversely affect male fertility by injuring testicular cells or instigate hormonal changes that lead to decreased semen quality (Figure 1) thereby compromising the pro...
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ژورنال
عنوان ژورنال: Toxicology Research
سال: 2018
ISSN: 2045-452X,2045-4538
DOI: 10.1039/c8tx00146d